Mechanisms in blood coagulation, fibrinolysis and complement system

Proteolytic enzymes in coagulation, fibrinolysis, and complement activation. Part A. Mammalian blood coagulation factors and inhibitors.

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Blood coagulation, fibrinolysis and exercise.

Activation of coagulation, anti-coagulation, fibrinolysis and the complement system in patients with urticaria.

BACKGROUND Recently released studies indicate that activation of blood coagulation may be involved in causing urticaria. OBJECTIVE To evaluate whether or not anticoagulation, fibrinolysis and the complement system are also involved in the pathogenesis of urticaria. METHODS Coagulant factors, anticoagulant factors, fibrinolytic markers and complement components were analysed in patients with...

Blood Coagulation, Fibrinolysis and Cellular Haemostasis Introduction

A high plasma concentration of coagulation factor VIII (FVIII) is an important risk factor for venous thromboembolism (VTE) (1-4). In the Leiden Thrombophilia study for example, FVIII levels above 1500 IU/L conferred an almost 5-fold risk for a first episode of deep-vein thrombosis (1). Most importantly, high FVIII is also associated with a very high risk of recurrent venous thromboembolism (4,...

Fibrinolysis and the control of blood coagulation.

Fibrin plays an essential role in hemostasis as both the primary product of the coagulation cascade and the ultimate substrate for fibrinolysis. Fibrinolysis efficiency is greatly influenced by clot structure, fibrinogen isoforms and polymorphisms, the rate of thrombin generation, the reactivity of thrombus-associated cells such as platelets, and the overall biochemical environment. Regulation ...